Shenglin Ma Selected Research

Tyrosine Kinase Inhibitors

1/2023	The second-generation tyrosine kinase inhibitor afatinib inhibits IL-1β secretion via blocking assembly of NLRP3 inflammasome independent of epidermal growth factor receptor signaling in macrophage.
1/2020	Timing in combination with radiotherapy and patterns of disease progression in non-small cell lung cancer treated with EGFR-TKI.
10/2018	Correction to: Comparison of the Amplification Refractory Mutation System, Super Amplification Refractory Mutation System, and Droplet Digital PCR for T790 M Mutation Detection in Non-small Cell Lung Cancer after Failure of Tyrosine Kinase Inhibitor Treatment.
10/2018	Comparison of the Amplification Refractory Mutation System, Super Amplification Refractory Mutation System, and Droplet Digital PCR for T790 M Mutation Detection in Non-small Cell Lung Cancer after Failure of Tyrosine Kinase Inhibitor Treatment.
1/2018	Mitochondrial pathway-mediated apoptosis is associated with erlotinib-induced cytotoxicity in hepatic cells.
1/2018	Epidermal growth factor receptor (EGFR) T790M mutation identified in plasma indicates failure sites and predicts clinical prognosis in non-small cell lung cancer progression during first-generation tyrosine kinase inhibitor therapy: a prospective observational study.
9/2017	Management of non-small cell lung cancer with EGFR mutation: the role of radiotherapy in the era of tyrosine kinase inhibitor therapy-opportunities and challenges.
1/2017	Intercalating and maintenance gefitinib plus chemotherapy versus chemotherapy alone in selected advanced non-small cell lung cancer with unknown EGFR status.
11/2016	Proteins associated with EGFR-TKIs resistance in patients with non-small cell lung cancer revealed by mass spectrometry.
3/2015	Afatinib increases sensitivity to radiation in non-small cell lung cancer cells with acquired EGFR T790M mutation.

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Shenglin Ma Research Topics

Disease

74	Neoplasms (Cancer) 02/2024 - 06/2009
53	Non-Small-Cell Lung Carcinoma (Carcinoma, Non-Small Cell Lung) 08/2023 - 05/2007
38	Lung Neoplasms (Lung Cancer) 01/2024 - 09/2010
19	Neoplasm Metastasis (Metastasis) 01/2023 - 08/2009
12	Adenocarcinoma of Lung 02/2023 - 08/2008
12	Disease Progression 01/2022 - 11/2008
10	Hyperthermia 01/2019 - 01/2011
8	Stomach Neoplasms (Stomach Cancer) 01/2024 - 11/2008
5	Ovarian Neoplasms (Ovarian Cancer) 05/2018 - 06/2009
4	Squamous Cell Carcinoma (Epidermoid Carcinoma) 12/2023 - 11/2018
4	Hypoxia (Hypoxemia) 03/2023 - 10/2014
4	Carcinoma (Carcinomatosis) 01/2023 - 11/2011
4	Pneumonia (Pneumonitis) 01/2023 - 05/2012
4	Diarrhea 01/2022 - 03/2014
4	Breast Neoplasms (Breast Cancer) 01/2022 - 01/2017
4	B-Cell Lymphoma (Lymphoma, B Cell) 01/2018 - 06/2014
3	Carcinogenesis 01/2024 - 11/2016
3	Colonic Neoplasms (Colon Cancer) 12/2022 - 09/2019
3	Brain Neoplasms (Brain Tumor) 01/2021 - 11/2012
3	Inflammation (Inflammations) 01/2021 - 01/2017
3	Asthma (Bronchial Asthma) 01/2019 - 11/2016
2	COVID-19 01/2023 - 01/2021
2	Sepsis (Septicemia) 01/2023 - 01/2021
2	Liver Diseases (Liver Disease) 01/2022 - 03/2015
2	Prostatic Neoplasms (Prostate Cancer) 01/2021 - 12/2015
2	Esophagitis 11/2019 - 09/2012
2	Acute Myeloid Leukemia (Acute Myelogenous Leukemia) 10/2019 - 01/2013
2	Respiratory Hypersensitivity 01/2019 - 01/2017
2	Lymphoma (Lymphomas) 11/2018 - 05/2015
2	Pancreatic Neoplasms (Pancreatic Cancer) 11/2018 - 01/2018
2	Malignant Pleural Effusion 01/2018 - 05/2017
2	Small Cell Lung Carcinoma (Small Cell Lung Cancer) 01/2016 - 05/2010
2	Exanthema (Rash) 03/2014 - 05/2012
2	Ovarian Epithelial Carcinoma 04/2013 - 06/2009

Drug/Important Bio-Agent (IBA)

22	Proteins (Proteins, Gene)FDA Link 01/2024 - 11/2009
16	ErbB Receptors (EGF Receptor)IBA 01/2024 - 03/2014
12	Gefitinib (Iressa)FDA Link 01/2021 - 08/2009
11	Tyrosine Kinase InhibitorsIBA 01/2023 - 03/2014
9	Biomarkers (Surrogate Marker)IBA 01/2023 - 01/2014
7	Therapeutic UsesIBA 11/2023 - 11/2011
6	Messenger RNA (mRNA)IBA 01/2019 - 06/2009
5	Phosphotransferases (Kinase)IBA 01/2024 - 11/2009
5	DNA (Deoxyribonucleic Acid)IBA 01/2023 - 04/2013
5	Vorinostat FDA Link 02/2021 - 01/2013
5	PlatinumIBA 01/2021 - 11/2008
5	Cisplatin (Platino)FDA LinkGeneric 01/2021 - 09/2010
5	Caspase 3 (Caspase-3)IBA 11/2018 - 06/2014
4	Immune Checkpoint InhibitorsIBA 10/2023 - 01/2019
4	Docetaxel (Taxotere)FDA Link 08/2023 - 11/2008
4	RNA (Ribonucleic Acid)IBA 06/2022 - 09/2010
4	osimertinibIBA 01/2022 - 01/2018
4	Histone Deacetylase InhibitorsIBA 02/2021 - 01/2013
4	Pemetrexed (MTA)FDA Link 01/2021 - 06/2011
4	Erlotinib Hydrochloride (CP 358,774)FDA Link 01/2021 - 09/2014
4	Gemcitabine FDA Link 11/2018 - 08/2008
3	licogliflozinIBA 01/2022 - 01/2019
3	MicroRNAs (MicroRNA)IBA 01/2021 - 01/2016
3	Carboplatin (JM8)FDA LinkGeneric 12/2019 - 06/2011
3	Paclitaxel (Taxol)FDA LinkGeneric 12/2019 - 06/2009
3	bcl-2-Associated X Protein (bcl 2 Associated X Protein)IBA 11/2018 - 01/2015
2	Reactive Oxygen Species (Oxygen Radicals)IBA 02/2024 - 11/2018
2	EnzymesIBA 01/2024 - 11/2018
2	IronIBA 12/2023 - 12/2023
2	pembrolizumabIBA 08/2023 - 01/2019
2	AfatinibIBA 01/2023 - 03/2015
2	ResveratrolIBA 12/2022 - 09/2019
2	larotrectinibIBA 11/2022 - 11/2022
2	AZD3759IBA 01/2022 - 12/2021
2	Circular RNAIBA 11/2021 - 01/2021
2	Bevacizumab (Avastin)FDA Link 01/2021 - 12/2019
2	Etoposide (VP 16)FDA LinkGeneric 01/2021 - 05/2015
2	SodiumIBA 01/2021 - 01/2019
2	Glucose (Dextrose)FDA LinkGeneric 01/2021 - 01/2019
2	Matrix Metalloproteinases (MMPs)IBA 01/2021 - 01/2018
2	Calcium-Calmodulin-Dependent Protein Kinase Type 2IBA 01/2021 - 11/2009
2	Vascular Endothelial Growth Factor A (Vascular Endothelial Growth Factor)IBA 12/2019 - 05/2015
2	Monoclonal AntibodiesIBA 12/2019 - 02/2014
2	Interleukin-4 (Interleukin 4)IBA 01/2019 - 01/2017
2	RetinoidsIBA 01/2019 - 11/2017
2	CytokinesIBA 01/2019 - 01/2017
2	Interleukin-5 (Interleukin 5)IBA 01/2019 - 01/2017
2	Mechanistic Target of Rapamycin Complex 1IBA 01/2019 - 01/2017
2	Caspase 9IBA 11/2018 - 06/2017
2	VimentinIBA 01/2018 - 01/2017
2	Small Interfering RNA (siRNA)IBA 01/2018 - 09/2010
2	Radiation-Sensitizing AgentsIBA 01/2018 - 03/2015
2	Long Noncoding RNAIBA 05/2017 - 09/2015
2	Protein-Tyrosine Kinases (Tyrosine Kinase)IBA 08/2016 - 01/2015
2	HSP70 Heat-Shock Proteins (Heat-Shock Protein 70)IBA 01/2016 - 01/2011
2	polyphyllin DIBA 01/2015 - 06/2014
2	StathminIBA 04/2013 - 06/2009

Therapy/Procedure

36	Radiotherapy 02/2023 - 05/2007
35	Therapeutics 02/2024 - 11/2008
30	Drug Therapy (Chemotherapy) 01/2022 - 05/2007
4	Immunotherapy 01/2023 - 01/2021
3	Chemoradiotherapy 11/2019 - 06/2011
3	Intensity-Modulated Radiotherapy (Radiotherapy, Intensity Modulated) 12/2018 - 01/2015
3	Cytoreduction Surgical Procedures 01/2015 - 06/2009
2	Oral Administration 01/2021 - 01/2019
2	Aftercare (After-Treatment) 10/2019 - 05/2017